[HTML][HTML] Mitochondrial oxidative phosphorylation complex regulates NLRP3 inflammasome activation and predicts patient survival in nasopharyngeal carcinoma
We previously reported that tumor inflammasomes play a key role in tumor control and act as
favorable prognostic markers in nasopharyngeal carcinoma (NPC). Activated
inflammasomes frequently form distinguishable specks and govern the cellular secretion of
IL-1β. However, we know little about the biological and biochemical differences between
cells with and without apoptosis-associated speck-like protein containing a caspase-
recruitment domain (ASC) speck formation. In this study, we used proteomic iTRAQ analysis …
favorable prognostic markers in nasopharyngeal carcinoma (NPC). Activated
inflammasomes frequently form distinguishable specks and govern the cellular secretion of
IL-1β. However, we know little about the biological and biochemical differences between
cells with and without apoptosis-associated speck-like protein containing a caspase-
recruitment domain (ASC) speck formation. In this study, we used proteomic iTRAQ analysis …