Pathology of post primary tuberculosis of the lung: an illustrated critical review
RL Hunter - Tuberculosis, 2011 - Elsevier
Post primary tuberculosis occurs in immunocompetent adults, is restricted to the lungs and
accounts for 80% of all clinical cases and nearly 100% of transmission of infection. The
supply of human tissues with post primary tuberculosis plummeted with the introduction of
antibiotics decades before the flowering of research using molecular methods in animal
models. Unfortunately, the paucity of human tissues prevented validation of the models. As a
result, it is a paradigm of contemporary research that caseating granulomas are the …
accounts for 80% of all clinical cases and nearly 100% of transmission of infection. The
supply of human tissues with post primary tuberculosis plummeted with the introduction of
antibiotics decades before the flowering of research using molecular methods in animal
models. Unfortunately, the paucity of human tissues prevented validation of the models. As a
result, it is a paradigm of contemporary research that caseating granulomas are the …
