[PDF][PDF] The rise of molecular glues

SL Schreiber - Cell, 2021 - cell.com
SL Schreiber
Cell, 2021cell.com
2021 marks the 30th anniversary of the revelation that cyclosporin A and FK506 act in a way
previously not seen—as" molecular glues" that induce neo-protein–protein associations. As
a torrent of new molecular-glue probes and medicines are fueling interest in this field, I
explore the arc of this story.
2021 marks the 30th anniversary of the revelation that cyclosporin A and FK506 act in a way previously not seen—as "molecular glues" that induce neo-protein–protein associations. As a torrent of new molecular-glue probes and medicines are fueling interest in this field, I explore the arc of this story.
cell.com