[HTML][HTML] How could HIV-1 drug resistance impact preexposure prophylaxis for HIV prevention?
UM Parikh, JW Mellors - Current Opinion in HIV and AIDS, 2022 - journals.lww.com
UM Parikh, JW Mellors
Current Opinion in HIV and AIDS, 2022•journals.lww.comPrEP is highly effective in preventing HIV infection. Although HIV drug resistance from PrEP
use could impact future options in individuals who seroconvert on PrEP, the current risk is
low and continued monitoring for the emergence of resistance and cross-resistance during
product development, clinical studies, and product roll-out is advised to preserve
antiretroviral efficacy for both treatment and prevention.
use could impact future options in individuals who seroconvert on PrEP, the current risk is
low and continued monitoring for the emergence of resistance and cross-resistance during
product development, clinical studies, and product roll-out is advised to preserve
antiretroviral efficacy for both treatment and prevention.
Summary
PrEP is highly effective in preventing HIV infection. Although HIV drug resistance from PrEP use could impact future options in individuals who seroconvert on PrEP, the current risk is low and continued monitoring for the emergence of resistance and cross-resistance during product development, clinical studies, and product roll-out is advised to preserve antiretroviral efficacy for both treatment and prevention.
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