Sir,? My attention has been drawn to the article by Dr. SC Nag, entitled" Notes on the Use of Carbon Tetrachloride," published in your journal for December, 1929, which describes various toxic symp-toms that in his cases arose after the administration of this drug. The discussion at the end of the article leaves it open to doubt whether these symptoms may possibly be attributed to impurities in the drug used. Since this latter was Carbon Tetrachloride" Merck," the whole matter was placed in the hands of my Analytical and Pharmacological Laboratories for comment. They now report that in their opinion the toxic effects observed cannot possibly be attributed to the Carbon Tetrachloride" Merck." This preparation is manufactured to conform with the requirements of all pharmacopoeias. Apart from this, it undergoes further tests to guarantee its complete freedom from chlorine, carbon disulphide, phosgene and other organic impurities; additional tests are made regarding its specific gravity and boiling point.