Vascularization and innervation of the islet of Langerhans are highly interconnected and are
critical for intercellular and intertissular communication. They are both involved in the control
of islet blood flow which has been shown to have an important role in the control of endocine
secretion. Both parameters are disturbed during the course of metabolic pathologies and
particularly diabetes. A better understanding of these mechanisms has and will greatly
benefit from the rapidly-emerging technologies particularly in vivo imaging enabling to study …